Sex- and age-related differences of HRQOL change in cardiac rehabilitation

Abstract Introduction Health-related quality of life (HRQOL) has emerged as a valid and disease-specific outcome measure in cardiac patients. Cardiac rehabilitation (CR), core component secondary prevention, not only improves cardiovascular outcomes, but also HRQOL. Unfortunately, CR is still underutilized, especially among women older Aim this study was to highlight age- sex-specific effects on Method A sample 8286 patients (mean age 69.2±11.47 years; men 67.8±11.29, 72.2±11.25) analyzed. Patients were prospectively asessed from 2012 2018 six Swiss clinics. HRQOL measured at entry discharge using the MacNew Heart Disease questionnaire. In multivariate analyses, we estimated sex- age-specific changes during CR, adjusting for clinical characteristics. Results Women scored lower any subdomain admission (social M = 5.05 (SD 1.3); emotional 5.06±1.17; physical 4.36±1.72), compared 5.2±1.23); 5.35±1.1; 4.43±1.76). showed greater improvement social (F=10.98, p<0.001), (F=17.73, p<0.001) (F=9.47, p=0.002). subgroup elderly (>76 years) female sex predicted higher (F=10.878, (F=1.424, p=0.232) (F=2.272, p=0.132). Conclusion report poorer all subdomains men, turn particularly benefit regard. patients, true Our results indicate that needs should be considered CR. Funding Acknowledgement Type funding sources: None.